A new anti-cancer drug against ovarian cancer (and other cancers) ? Ovarian cancer, the silent killer, is the leading cause of death from gynecologic cancer. The cancer is mostly manifested at advanced stage ( Stage III, IV), having spread beyond the ovaries to involve the peritoneal cavity.
The leaves of C. amaranthoides were extracted and then fractionated by column chromatography.
Two compounds were isolated by chromatographic fractionation and identified by nuclear magnetic resonance (1H-NMR, 13C-NMR) and mass spectrometry analyses.
van Haaften and Tran: Efficient isolation of an anti-cancer sesquiterpene lactone from Calomeria amaranthoides. Green and Sustainable Chemistry 2011, 1: 123-127
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Calomeria amaranthoides is a tall, fragrant biennial herb, growing to 3.5 metres in height. It has sticky stems and leaves which are green above and whitish beneath and are up to 15 cm long and 5 cm wide. Its flowers appear in large brown to red plumes in the summer (January to April in its native range)